N,N-Dimethyl-2-PhenylethylaMine Hydrochloride CAS 10275-21-5


Product  NameN,N-diMethyl-2-phenylethylaMine  hydrochloride
CAS NO10275-21-5
Molecular FormulaC10H16ClN
Molecular Weight185.69
Melting point 200-201.5(lit.)
Boiling Point207.3oC at 760mmHg
Flash Point71.4oC
Density N/A
GradePharmaceutical Grade
SolubilityDMF: 30mg/mL
DMSO: 30mg/mL
Ethanol: 25mg/mL
PBS (pH 7.2): 10mg/mL
AppearanceA crystalline solid
Packing and ShippingPacking: Drum / Aluminum Foil  Bag / According to customer's requiement                                                          Shipping: 3-5 working days after receive payment, by  Fedex,UPS,EMS,DHL,Sea and air transport
UsageIt is used in the synthesis of  squalene synthase inhibitors.

What is N,N-Dimethylphenethylamine (10275-21-5)

N,N-Dimethylphenethylamine (N,N-DMPEA) is a substituted phenethylamine that is used as a flavoring agent. It is an alkaloid that was first isolated from the orchid Eria jarensis.Its aroma is described as "sweet, fishy". It is mainly used in cereal, cheese, dairy products, fish, fruit and meat.It is also being used in pre-workout and bodybuilding supplements with claims of a stimulant effect.

There is also evidence suggesting that N,N-DMPEA acts as a TAAR1 agonist in humans, and as a 5-HT1A ligand in rats. Some less conclusive research also indicated that it had interaction with MAO-B, most likely as an enzyme substrate and not an inhibitor.

N,N-Dimethylphenethylamine (10275-21-5) Reference

1. K. Hedman, K. Leander and B. Luning (1969). "Studies on Orchidaceae Alkaloids. XV. Phenethylamines from Eria jarensis Ames". Acta Chem. Scand. 23: 3261. doi:10.3891/acta.chem.scand.23-3261.

2. Burdock, G.A. (2016). Fenaroli's Handbook of Flavor Ingredients, Sixth Edition. CRC Press. p. 499. ISBN 9781420090864. Retrieved 2016-09-13.

3."Eria Jarensis Extract / N-phenethyl dimethylamine: The Next Big Thing?". blog.priceplow.com. Retrieved 2016-10-05.

4.Wainscott DB, Little SP, Yin T, Tu Y, Rocco VP, He JX, Nelson DL (January 2007). "Pharmacologic characterization of the cloned human trace amine-associated receptor1 (TAAR1) and evidence for species differences with the rat TAAR1". The Journal of Pharmacology and Experimental Therapeutics. 320 (1): 475C485. doi:10.1124/jpet.106.112532. PMID 17038507. S2CID 10829497.


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